Avian influenza A(H5N1) Influenza A virus subtype H5N1
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza. It is enzootic in many bird populations, and also panzootic. A/H5N1 virus can also infect mammals that have been exposed to infected birds; in these cases, symptoms are frequently severe or fatal.
51WHO outbreaks
10,019Cases reported
774Deaths
10Countries affected
Countries with active outbreaks
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China — 24 events, 9,653 cases, 629 deaths
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Cambodia — 5 events, 143 cases, 134 deaths
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Italy — 3 events
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United States — 3 events
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Mexico — 3 events, 25 cases
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Spain — 2 events, 25 cases
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India — 2 events
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Chile — 2 events
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Canada — 1 events, 25 cases
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Ghana — 1 events
Recent events
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2026-04-10T13:51:44Z · Italy — Avian Influenza A(H9N2) - Italy
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2025-12-05T16:36:27Z · United States — Avian Influenza A(H5N5)- United States of America
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2025-07-05T05:41:27Z · Cambodia — Avian Influenza A(H5N1) - Cambodia · 11 cases · 12 deaths
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2025-04-17T18:08:00Z · Mexico — Avian Influenza A(H5N1) - Mexico · 25 cases
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2025-04-17T18:08:00Z · Spain — Avian Influenza A(H5N1) - Mexico · 25 cases
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2025-04-17T18:08:00Z · Canada — Avian Influenza A(H5N1) - Mexico · 25 cases
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2024-09-20T18:00:00Z · Ghana — Avian Influenza A(H9N2)
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2024-09-02T18:00:00Z · Cambodia — Avian Influenza A(H5N1)- Cambodia · 10 cases · 43 deaths
Frequently asked questions
What is Avian influenza A(H5N1)?
Avian influenza A(H5N1) is an infectious disease caused by Influenza A virus subtype H5N1. Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza. It is enzootic in many bird populations, and also panzootic. A/H5N1 virus can also infect mammals that have been exposed to infected birds; in these cases, symptoms are frequently severe or fatal.
How is Avian influenza A(H5N1) transmitted?
The main transmission routes of Avian influenza A(H5N1) are: zoonotic (poultry, dairy cattle), airborne (rare H2H).
Where is Avian influenza A(H5N1) endemic?
Avian influenza A(H5N1) is endemic in the following regions: Worldwide poultry/wildlife.
What is the case fatality rate of Avian influenza A(H5N1)?
The typical case fatality rate (CFR) of Avian influenza A(H5N1) is ~50%.
How many active Avian influenza A(H5N1) outbreaks worldwide?
Currently 51 active WHO outbreaks reported, with 10019 cases and 774 deaths in the surveillance window.
Official sources
Observium aggregates real-time data from authoritative sources:
WHO Disease Outbreak News,
CDC NNDSS,
ECDC,
Europe PMC,
Italian Ministry of Health, ISS,
UKHSA, RIVM, RKI, BAG, ISCIII, NICD,
and 20+ national sources plus Google News.
View all sources →