Creutzfeldt–Jakob disease (CJD) is an incurable, always fatal, neurodegenerative disease belonging to the transmissible spongiform encephalopathy (TSE) group. Early symptoms include memory problems, behavioral changes, poor coordination, visual disturbances and auditory disturbances. Later symptoms include dementia, involuntary movements, blindness, deafness, weakness, and coma. About 70% of sufferers die within a year of diagnosis. The name "Creutzfeldt–Jakob disease" was introduced by Walther Spielmeyer in 1922, after the German neurologists Hans Gerhard Creutzfeldt and Alfons Maria Jakob.
Creutzfeldt-Jakob disease (CJD) is an infectious disease caused by Misfolded PrP. Creutzfeldt–Jakob disease (CJD) is an incurable, always fatal, neurodegenerative disease belonging to the transmissible spongiform encephalopathy (TSE) group. Early symptoms include memory problems, behavioral changes, poor coordination, visual disturbances and auditory disturbances. Later symptoms include dementia, involuntary movements, blindness, deafness, weakness, and coma. About 70% of suffe
The main transmission routes of Creutzfeldt-Jakob disease (CJD) are: sporadic, iatrogenic, vCJD: BSE-contaminated beef.
Creutzfeldt-Jakob disease (CJD) is endemic in the following regions: Worldwide sporadic, vCJD UK historically.
The typical case fatality rate (CFR) of Creutzfeldt-Jakob disease (CJD) is 100%.
Currently 0 active WHO outbreaks reported, with None cases and None deaths in the surveillance window.
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