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Observium Creutzfeldt-Jakob disease (CJD)

Creutzfeldt-Jakob disease (CJD) Misfolded PrP

Creutzfeldt–Jakob disease (CJD) is an incurable, always fatal, neurodegenerative disease belonging to the transmissible spongiform encephalopathy (TSE) group. Early symptoms include memory problems, behavioral changes, poor coordination, visual disturbances and auditory disturbances. Later symptoms include dementia, involuntary movements, blindness, deafness, weakness, and coma. About 70% of sufferers die within a year of diagnosis. The name "Creutzfeldt–Jakob disease" was introduced by Walther Spielmeyer in 1922, after the German neurologists Hans Gerhard Creutzfeldt and Alfons Maria Jakob.

0WHO outbreaks
0Cases reported
0Deaths
0Countries affected

Frequently asked questions

What is Creutzfeldt-Jakob disease (CJD)?

Creutzfeldt-Jakob disease (CJD) is an infectious disease caused by Misfolded PrP. Creutzfeldt–Jakob disease (CJD) is an incurable, always fatal, neurodegenerative disease belonging to the transmissible spongiform encephalopathy (TSE) group. Early symptoms include memory problems, behavioral changes, poor coordination, visual disturbances and auditory disturbances. Later symptoms include dementia, involuntary movements, blindness, deafness, weakness, and coma. About 70% of suffe

How is Creutzfeldt-Jakob disease (CJD) transmitted?

The main transmission routes of Creutzfeldt-Jakob disease (CJD) are: sporadic, iatrogenic, vCJD: BSE-contaminated beef.

Where is Creutzfeldt-Jakob disease (CJD) endemic?

Creutzfeldt-Jakob disease (CJD) is endemic in the following regions: Worldwide sporadic, vCJD UK historically.

What is the case fatality rate of Creutzfeldt-Jakob disease (CJD)?

The typical case fatality rate (CFR) of Creutzfeldt-Jakob disease (CJD) is 100%.

How many active Creutzfeldt-Jakob disease (CJD) outbreaks worldwide?

Currently 0 active WHO outbreaks reported, with None cases and None deaths in the surveillance window.

Official sources

Observium aggregates real-time data from authoritative sources: WHO Disease Outbreak News, CDC NNDSS, ECDC, Europe PMC, Italian Ministry of Health, ISS, UKHSA, RIVM, RKI, BAG, ISCIII, NICD, and 20+ national sources plus Google News.

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